PLaTITO: Protein Language Model Embeddings Improve Generalization of Implicit Transfer Operators

Paper: arXiv:2602.11216 | Code: github.com/PanosAntoniadis/platito

PLaTITO is a transferable implicit transfer operator for coarse-grained protein molecular dynamics that conditions on protein language model embeddings to improve its data efficiency and generalization.

File	Parameters	ESM backbone
tito_3M.ckpt	3M	—
platito_3M.ckpt	3M	ESMC 300M
platito_19M.ckpt	19M	ESMC 6B
platito_36M.ckpt	36M	ESMC 6B

Citing This Model

@article{antoniadis2026platito,
  title={Protein Language Model Embeddings Improve Generalization of Implicit Transfer Operators},
  author={Antoniadis, Panagiotis and Pavesi, Beatrice and Olsson, Simon and Winther, Ole},
  journal={arXiv e-prints},
  pages={arXiv--2602},
  year={2026}
}