messages listlengths 2 2 | metadata dict | tools listlengths 6 6 |
|---|---|---|
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{
"content": "You are an expert for evaluating the strength of evidence supporting a monogenic gene–disease relationship in literature based on biochemical function. \nLook for any evidence showing that the gene product of SMAD2 performs a biochemical function:\n(A) shared with other known genes in the disease ... | {
"agent_name": "ExperimentalEvidence.BiochemicalFunction",
"disease": "congenital heart disease",
"gene": "SMAD2",
"pmid": "33801433",
"run_id": "df09e6436eb84e6cb430f9b469183bc8",
"trace_id": "df09e6436eb84e6cb430f9b469183bc8"
} | [
{
"function": {
"description": "Analyse experimentalevidence biochemicalfunction evidence from PubMed Article.",
"name": "ExperimentalEvidence_BiochemicalFunction_agent",
"parameters": {
"properties": {
"disease": {
"type": "string"
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"gene": ... |
[
{
"content": "You are an expert for evaluating the strength of evidence supporting a monogenic gene–disease relationship in literature based on biochemical function. \nLook for any evidence showing that the gene product of LZTFL1 performs a biochemical function:\n(A) shared with other known genes in the disease... | {
"agent_name": "ExperimentalEvidence.BiochemicalFunction",
"disease": "LZTFL1-related ciliopathy",
"gene": "LZTFL1",
"pmid": "22072986",
"run_id": "496c3907a87a4e1eb7b2665b54afad4c",
"trace_id": "496c3907a87a4e1eb7b2665b54afad4c"
} | [
{
"function": {
"description": "Analyse experimentalevidence biochemicalfunction evidence from PubMed Article.",
"name": "ExperimentalEvidence_BiochemicalFunction_agent",
"parameters": {
"properties": {
"disease": {
"type": "string"
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"gene": ... |
[
{
"content": "You are an expert for evaluating the strength of evidence supporting a monogenic gene–disease relationship in literature based on biochemical function. \nLook for any evidence showing that the gene product of LTBP2 performs a biochemical function:\n(A) shared with other known genes in the disease ... | {
"agent_name": "ExperimentalEvidence.BiochemicalFunction",
"disease": "glaucoma 3, primary congenital, D",
"gene": "LTBP2",
"pmid": "27149523",
"run_id": "73e6551750a24b2a85bc25d00919597b",
"trace_id": "73e6551750a24b2a85bc25d00919597b"
} | [
{
"function": {
"description": "Analyse experimentalevidence biochemicalfunction evidence from PubMed Article.",
"name": "ExperimentalEvidence_BiochemicalFunction_agent",
"parameters": {
"properties": {
"disease": {
"type": "string"
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"gene": ... |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"lysosomal acid lipase deficiency(...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"hypercholesterolemia, familial, (...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"congenital disorder of glycosyla(...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"COG1-congenital disorder of glyc(...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"COG1-congenital disorder of glyc(...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"pulmonary arterial hypertension"(...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
[{"content":"You are an expert for evaluating the strength of evidence supporting a monogenic gene(...TRUNCATED) | {"agent_name":"ExperimentalEvidence.BiochemicalFunction","disease":"pulmonary arterial hypertension"(...TRUNCATED) | [{"function":{"description":"Analyse experimentalevidence biochemicalfunction evidence from PubMed A(...TRUNCATED) |
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