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Dec 31

Frozen-DETR: Enhancing DETR with Image Understanding from Frozen Foundation Models

Recent vision foundation models can extract universal representations and show impressive abilities in various tasks. However, their application on object detection is largely overlooked, especially without fine-tuning them. In this work, we show that frozen foundation models can be a versatile feature enhancer, even though they are not pre-trained for object detection. Specifically, we explore directly transferring the high-level image understanding of foundation models to detectors in the following two ways. First, the class token in foundation models provides an in-depth understanding of the complex scene, which facilitates decoding object queries in the detector's decoder by providing a compact context. Additionally, the patch tokens in foundation models can enrich the features in the detector's encoder by providing semantic details. Utilizing frozen foundation models as plug-and-play modules rather than the commonly used backbone can significantly enhance the detector's performance while preventing the problems caused by the architecture discrepancy between the detector's backbone and the foundation model. With such a novel paradigm, we boost the SOTA query-based detector DINO from 49.0% AP to 51.9% AP (+2.9% AP) and further to 53.8% AP (+4.8% AP) by integrating one or two foundation models respectively, on the COCO validation set after training for 12 epochs with R50 as the detector's backbone.

  • 6 authors
·
Oct 25, 2024

FrozenSeg: Harmonizing Frozen Foundation Models for Open-Vocabulary Segmentation

Open-vocabulary segmentation poses significant challenges, as it requires segmenting and recognizing objects across an open set of categories in unconstrained environments. Building on the success of powerful vision-language (ViL) foundation models, such as CLIP, recent efforts sought to harness their zero-short capabilities to recognize unseen categories. Despite notable performance improvements, these models still encounter the critical issue of generating precise mask proposals for unseen categories and scenarios, resulting in inferior segmentation performance eventually. To address this challenge, we introduce a novel approach, FrozenSeg, designed to integrate spatial knowledge from a localization foundation model (e.g., SAM) and semantic knowledge extracted from a ViL model (e.g., CLIP), in a synergistic framework. Taking the ViL model's visual encoder as the feature backbone, we inject the space-aware feature into the learnable queries and CLIP features within the transformer decoder. In addition, we devise a mask proposal ensemble strategy for further improving the recall rate and mask quality. To fully exploit pre-trained knowledge while minimizing training overhead, we freeze both foundation models, focusing optimization efforts solely on a lightweight transformer decoder for mask proposal generation-the performance bottleneck. Extensive experiments demonstrate that FrozenSeg advances state-of-the-art results across various segmentation benchmarks, trained exclusively on COCO panoptic data, and tested in a zero-shot manner. Code is available at https://github.com/chenxi52/FrozenSeg.

  • 5 authors
·
Sep 5, 2024 2

Autonomous labeling of surgical resection margins using a foundation model

Assessing resection margins is central to pathological specimen evaluation and has profound implications for patient outcomes. Current practice employs physical inking, which is applied variably, and cautery artifacts can obscure the true margin on histological sections. We present a virtual inking network (VIN) that autonomously localizes the surgical cut surface on whole-slide images, reducing reliance on inks and standardizing margin-focused review. VIN uses a frozen foundation model as the feature extractor and a compact two-layer multilayer perceptron trained for patch-level classification of cautery-consistent features. The dataset comprised 120 hematoxylin and eosin (H&E) stained slides from 12 human tonsil tissue blocks, resulting in ~2 TB of uncompressed raw image data, where a board-certified pathologist provided boundary annotations. In blind testing with 20 slides from previously unseen blocks, VIN produced coherent margin overlays that qualitatively aligned with expert annotations across serial sections. Quantitatively, region-level accuracy was ~73.3% across the test set, with errors largely confined to limited areas that did not disrupt continuity of the whole-slide margin map. These results indicate that VIN captures cautery-related histomorphology and can provide a reproducible, ink-free margin delineation suitable for integration into routine digital pathology workflows and for downstream measurement of margin distances.

  • 12 authors
·
Nov 27

Efficient Adapter Finetuning for Tail Languages in Streaming Multilingual ASR

The end-to-end ASR model is often desired in the streaming multilingual scenario since it is easier to deploy and can benefit from pre-trained speech models such as powerful foundation models. Meanwhile, the heterogeneous nature and imbalanced data abundance of different languages may cause performance degradation, leading to asynchronous peak performance for different languages during training, especially on tail ones. Sometimes even the data itself may become unavailable as a result of the enhanced privacy protection. Existing work tend to significantly increase the model size or learn language-specific decoders to accommodate each language separately. In this study, we explore simple yet effective Language-Dependent Adapter (LDA) finetuning under a cascaded Conformer transducer framework enhanced by teacher pseudo-labeling for tail languages in the streaming multilingual ASR. The adapter only accounts for 0.4% of the full model per language. It is plugged into the frozen foundation model and is the only trainable module during the finetuning process with noisy student training. The final model merges the adapter parameters from different checkpoints for different languages. The model performance is validated on a challenging multilingual dictation dataset, which includes 39 tail languages across Latin, Greek, Arabic, etc. Our proposed method brings 12.2% word error rate reduction on average and up to 37.5% on a single locale. Furthermore, we show that our parameter-efficient LDA can match the quality of the full model finetuning, thus greatly alleviating the asynchronous peak performance issue.

  • 5 authors
·
Jan 17, 2024

Redefining Generalization in Visual Domains: A Two-Axis Framework for Fake Image Detection with FusionDetect

The rapid development of generative models has made it increasingly crucial to develop detectors that can reliably detect synthetic images. Although most of the work has now focused on cross-generator generalization, we argue that this viewpoint is too limited. Detecting synthetic images involves another equally important challenge: generalization across visual domains. To bridge this gap,we present the OmniGen Benchmark. This comprehensive evaluation dataset incorporates 12 state-of-the-art generators, providing a more realistic way of evaluating detector performance under realistic conditions. In addition, we introduce a new method, FusionDetect, aimed at addressing both vectors of generalization. FusionDetect draws on the benefits of two frozen foundation models: CLIP & Dinov2. By deriving features from both complementary models,we develop a cohesive feature space that naturally adapts to changes in both thecontent and design of the generator. Our extensive experiments demonstrate that FusionDetect delivers not only a new state-of-the-art, which is 3.87% more accurate than its closest competitor and 6.13% more precise on average on established benchmarks, but also achieves a 4.48% increase in accuracy on OmniGen,along with exceptional robustness to common image perturbations. We introduce not only a top-performing detector, but also a new benchmark and framework for furthering universal AI image detection. The code and dataset are available at http://github.com/amir-aman/FusionDetect

  • 4 authors
·
Oct 7

Objects matter: object-centric world models improve reinforcement learning in visually complex environments

Deep reinforcement learning has achieved remarkable success in learning control policies from pixels across a wide range of tasks, yet its application remains hindered by low sample efficiency, requiring significantly more environment interactions than humans to reach comparable performance. Model-based reinforcement learning (MBRL) offers a solution by leveraging learnt world models to generate simulated experience, thereby improving sample efficiency. However, in visually complex environments, small or dynamic elements can be critical for decision-making. Yet, traditional MBRL methods in pixel-based environments typically rely on auto-encoding with an L_2 loss, which is dominated by large areas and often fails to capture decision-relevant details. To address these limitations, we propose an object-centric MBRL pipeline, which integrates recent advances in computer vision to allow agents to focus on key decision-related elements. Our approach consists of four main steps: (1) annotating key objects related to rewards and goals with segmentation masks, (2) extracting object features using a pre-trained, frozen foundation vision model, (3) incorporating these object features with the raw observations to predict environmental dynamics, and (4) training the policy using imagined trajectories generated by this object-centric world model. Building on the efficient MBRL algorithm STORM, we call this pipeline OC-STORM. We demonstrate OC-STORM's practical value in overcoming the limitations of conventional MBRL approaches on both Atari games and the visually complex game Hollow Knight.

  • 4 authors
·
Jan 27

FantasyWorld: Geometry-Consistent World Modeling via Unified Video and 3D Prediction

High-quality 3D world models are pivotal for embodied intelligence and Artificial General Intelligence (AGI), underpinning applications such as AR/VR content creation and robotic navigation. Despite the established strong imaginative priors, current video foundation models lack explicit 3D grounding capabilities, thus being limited in both spatial consistency and their utility for downstream 3D reasoning tasks. In this work, we present FantasyWorld, a geometry-enhanced framework that augments frozen video foundation models with a trainable geometric branch, enabling joint modeling of video latents and an implicit 3D field in a single forward pass. Our approach introduces cross-branch supervision, where geometry cues guide video generation and video priors regularize 3D prediction, thus yielding consistent and generalizable 3D-aware video representations. Notably, the resulting latents from the geometric branch can potentially serve as versatile representations for downstream 3D tasks such as novel view synthesis and navigation, without requiring per-scene optimization or fine-tuning. Extensive experiments show that FantasyWorld effectively bridges video imagination and 3D perception, outperforming recent geometry-consistent baselines in multi-view coherence and style consistency. Ablation studies further confirm that these gains stem from the unified backbone and cross-branch information exchange.

  • 5 authors
·
Sep 25

Weak Cube R-CNN: Weakly Supervised 3D Detection using only 2D Bounding Boxes

Monocular 3D object detection is an essential task in computer vision, and it has several applications in robotics and virtual reality. However, 3D object detectors are typically trained in a fully supervised way, relying extensively on 3D labeled data, which is labor-intensive and costly to annotate. This work focuses on weakly-supervised 3D detection to reduce data needs using a monocular method that leverages a singlecamera system over expensive LiDAR sensors or multi-camera setups. We propose a general model Weak Cube R-CNN, which can predict objects in 3D at inference time, requiring only 2D box annotations for training by exploiting the relationship between 2D projections of 3D cubes. Our proposed method utilizes pre-trained frozen foundation 2D models to estimate depth and orientation information on a training set. We use these estimated values as pseudo-ground truths during training. We design loss functions that avoid 3D labels by incorporating information from the external models into the loss. In this way, we aim to implicitly transfer knowledge from these large foundation 2D models without having access to 3D bounding box annotations. Experimental results on the SUN RGB-D dataset show increased performance in accuracy compared to an annotation time equalized Cube R-CNN baseline. While not precise for centimetre-level measurements, this method provides a strong foundation for further research.

  • 3 authors
·
Apr 17

Q-Former Autoencoder: A Modern Framework for Medical Anomaly Detection

Anomaly detection in medical images is an important yet challenging task due to the diversity of possible anomalies and the practical impossibility of collecting comprehensively annotated data sets. In this work, we tackle unsupervised medical anomaly detection proposing a modernized autoencoder-based framework, the Q-Former Autoencoder, that leverages state-of-the-art pretrained vision foundation models, such as DINO, DINOv2 and Masked Autoencoder. Instead of training encoders from scratch, we directly utilize frozen vision foundation models as feature extractors, enabling rich, multi-stage, high-level representations without domain-specific fine-tuning. We propose the usage of the Q-Former architecture as the bottleneck, which enables the control of the length of the reconstruction sequence, while efficiently aggregating multiscale features. Additionally, we incorporate a perceptual loss computed using features from a pretrained Masked Autoencoder, guiding the reconstruction towards semantically meaningful structures. Our framework is evaluated on four diverse medical anomaly detection benchmarks, achieving state-of-the-art results on BraTS2021, RESC, and RSNA. Our results highlight the potential of vision foundation model encoders, pretrained on natural images, to generalize effectively to medical image analysis tasks without further fine-tuning. We release the code and models at https://github.com/emirhanbayar/QFAE.

  • 4 authors
·
Jul 24

Recognize Any Regions

Understanding the semantics of individual regions or patches within unconstrained images, such as in open-world object detection, represents a critical yet challenging task in computer vision. Building on the success of powerful image-level vision-language (ViL) foundation models like CLIP, recent efforts have sought to harness their capabilities by either training a contrastive model from scratch with an extensive collection of region-label pairs or aligning the outputs of a detection model with image-level representations of region proposals. Despite notable progress, these approaches are plagued by computationally intensive training requirements, susceptibility to data noise, and deficiency in contextual information. To address these limitations, we explore the synergistic potential of off-the-shelf foundation models, leveraging their respective strengths in localization and semantics. We introduce a novel, generic, and efficient region recognition architecture, named RegionSpot, designed to integrate position-aware localization knowledge from a localization foundation model (e.g., SAM) with semantic information extracted from a ViL model (e.g., CLIP). To fully exploit pretrained knowledge while minimizing training overhead, we keep both foundation models frozen, focusing optimization efforts solely on a lightweight attention-based knowledge integration module. Through extensive experiments in the context of open-world object recognition, our RegionSpot demonstrates significant performance improvements over prior alternatives, while also providing substantial computational savings. For instance, training our model with 3 million data in a single day using 8 V100 GPUs. Our model outperforms GLIP by 6.5 % in mean average precision (mAP), with an even larger margin by 14.8 % for more challenging and rare categories.

  • 6 authors
·
Nov 2, 2023

CoRA: Covariate-Aware Adaptation of Time Series Foundation Models

Time Series Foundation Models (TSFMs) have shown significant impact through their model capacity, scalability, and zero-shot generalization. However, due to the heterogeneity of inter-variate dependencies and the backbone scalability on large-scale multivariate datasets, most TSFMs are typically pre-trained on univariate time series. This limitation renders them oblivious to crucial information from diverse covariates in real-world forecasting tasks. To further enhance the performance of TSFMs, we propose a general covariate-aware adaptation (CoRA) framework for TSFMs. It leverages pre-trained backbones of foundation models while effectively incorporating exogenous covariates from various modalities, including time series, language, and images, to improve the quality of predictions. Technically, CoRA maintains the equivalence of initialization and parameter consistency during adaptation. With preserved backbones of foundation models as frozen feature extractors, the outcome embeddings from foundation models are empirically demonstrated more informative than raw data. Further, CoRA employs a novel Granger Causality Embedding (GCE) to automatically evaluate covariates regarding their causal predictability with respect to the target variate. We incorporate these weighted embeddings with a zero-initialized condition-injection mechanism, avoiding catastrophic forgetting of pre-trained foundation models and gradually integrates exogenous information. Extensive experiments show that CoRA of TSFMs surpasses state-of-the-art covariate-aware deep forecasters with full or few-shot training samples, achieving 31.1% MSE reduction on covariate-aware forecasting. Compared to other adaptation methods, CoRA exhibits strong compatibility with various advanced TSFMs and extends the scope of covariates to other modalities, presenting a practical paradigm for the application of TSFMs.

  • 8 authors
·
Oct 14

InternVideo-Next: Towards General Video Foundation Models without Video-Text Supervision

Large-scale video-text pretraining achieves strong performance but depends on noisy, synthetic captions with limited semantic coverage, often overlooking implicit world knowledge such as object motion, 3D geometry, and physical cues. In contrast, masked video modeling (MVM) directly exploits spatiotemporal structures but trails text-supervised methods on general tasks. We find this gap arises from overlooked architectural issues: pixel-level reconstruction struggles with convergence and its low-level requirement often conflicts with semantics, while latent prediction often encourages shortcut learning. To address these, we disentangle the traditional encoder-decoder design into an Encoder-Predictor-Decoder (EPD) framework, where the predictor acts as a latent world model, and propose InternVideo-Next, a two-stage pretraining scheme that builds a semantically consistent yet detail-preserving latent space for this world model. First, conventional linear decoder in pixel MVM enforces the predictor output latent to be linearly projected to, thus separable in pixel space, causing the conflict with semantic abstraction. Our Stage 1 proposes a conditional diffusion decoder and injects reliable image-level semantic priors to enhance semantics and convergence, thus bridging pixel-level fidelity with high-level semantic abstraction. Stage 2 further learns world knowledge by predicting frozen Stage 1 targets within this space, mitigating shortcut learning. Trained on public, unlabeled videos, InternVideo-Next achieves state-of-the-art results across benchmarks and provides a scalable path toward general video representation learning.

OpenGVLab OpenGVLab
·
Dec 1 1

Adapting Vision Foundation Models for Robust Cloud Segmentation in Remote Sensing Images

Cloud segmentation is a critical challenge in remote sensing image interpretation, as its accuracy directly impacts the effectiveness of subsequent data processing and analysis. Recently, vision foundation models (VFM) have demonstrated powerful generalization capabilities across various visual tasks. In this paper, we present a parameter-efficient adaptive approach, termed Cloud-Adapter, designed to enhance the accuracy and robustness of cloud segmentation. Our method leverages a VFM pretrained on general domain data, which remains frozen, eliminating the need for additional training. Cloud-Adapter incorporates a lightweight spatial perception module that initially utilizes a convolutional neural network (ConvNet) to extract dense spatial representations. These multi-scale features are then aggregated and serve as contextual inputs to an adapting module, which modulates the frozen transformer layers within the VFM. Experimental results demonstrate that the Cloud-Adapter approach, utilizing only 0.6% of the trainable parameters of the frozen backbone, achieves substantial performance gains. Cloud-Adapter consistently attains state-of-the-art (SOTA) performance across a wide variety of cloud segmentation datasets from multiple satellite sources, sensor series, data processing levels, land cover scenarios, and annotation granularities. We have released the source code and pretrained models at https://github.com/XavierJiezou/Cloud-Adapter to support further research.

  • 8 authors
·
Nov 20, 2024 2

Fine-tuning of Geospatial Foundation Models for Aboveground Biomass Estimation

Global vegetation structure mapping is critical for understanding the global carbon cycle and maximizing the efficacy of nature-based carbon sequestration initiatives. Moreover, vegetation structure mapping can help reduce the impacts of climate change by, for example, guiding actions to improve water security, increase biodiversity and reduce flood risk. Global satellite measurements provide an important set of observations for monitoring and managing deforestation and degradation of existing forests, natural forest regeneration, reforestation, biodiversity restoration, and the implementation of sustainable agricultural practices. In this paper, we explore the effectiveness of fine-tuning of a geospatial foundation model to estimate above-ground biomass (AGB) using space-borne data collected across different eco-regions in Brazil. The fine-tuned model architecture consisted of a Swin-B transformer as the encoder (i.e., backbone) and a single convolutional layer for the decoder head. All results were compared to a U-Net which was trained as the baseline model Experimental results of this sparse-label prediction task demonstrate that the fine-tuned geospatial foundation model with a frozen encoder has comparable performance to a U-Net trained from scratch. This is despite the fine-tuned model having 13 times less parameters requiring optimization, which saves both time and compute resources. Further, we explore the transfer-learning capabilities of the geospatial foundation models by fine-tuning on satellite imagery with sparse labels from different eco-regions in Brazil.

  • 16 authors
·
Jun 28, 2024

Dino U-Net: Exploiting High-Fidelity Dense Features from Foundation Models for Medical Image Segmentation

Foundation models pre-trained on large-scale natural image datasets offer a powerful paradigm for medical image segmentation. However, effectively transferring their learned representations for precise clinical applications remains a challenge. In this work, we propose Dino U-Net, a novel encoder-decoder architecture designed to exploit the high-fidelity dense features of the DINOv3 vision foundation model. Our architecture introduces an encoder built upon a frozen DINOv3 backbone, which employs a specialized adapter to fuse the model's rich semantic features with low-level spatial details. To preserve the quality of these representations during dimensionality reduction, we design a new fidelity-aware projection module (FAPM) that effectively refines and projects the features for the decoder. We conducted extensive experiments on seven diverse public medical image segmentation datasets. Our results show that Dino U-Net achieves state-of-the-art performance, consistently outperforming previous methods across various imaging modalities. Our framework proves to be highly scalable, with segmentation accuracy consistently improving as the backbone model size increases up to the 7-billion-parameter variant. The findings demonstrate that leveraging the superior, dense-pretrained features from a general-purpose foundation model provides a highly effective and parameter-efficient approach to advance the accuracy of medical image segmentation. The code is available at https://github.com/yifangao112/DinoUNet.

  • 5 authors
·
Aug 28

Breaking Data Silos: Towards Open and Scalable Mobility Foundation Models via Generative Continual Learning

Foundation models have revolutionized fields such as natural language processing and computer vision by enabling general-purpose learning across diverse tasks and datasets. However, building analogous models for human mobility remains challenging due to the privacy-sensitive nature of mobility data and the resulting data silos across institutions. To bridge this gap, we propose MoveGCL, a scalable and privacy-preserving framework for training mobility foundation models via generative continual learning. Without sharing raw data, MoveGCL enables decentralized and progressive model evolution by replaying synthetic trajectories generated from a frozen teacher model, and reinforces knowledge retention through a tailored distillation strategy that mitigates catastrophic forgetting. To address the heterogeneity of mobility patterns, MoveGCL incorporates a Mixture-of-Experts Transformer with a mobility-aware expert routing mechanism, and employs a layer-wise progressive adaptation strategy to stabilize continual updates. Experiments on six real-world urban datasets demonstrate that MoveGCL achieves performance comparable to joint training and significantly outperforms federated learning baselines, while offering strong privacy protection. MoveGCL marks a crucial step toward unlocking foundation models for mobility, offering a practical blueprint for open, scalable, and privacy-preserving model development in the era of foundation models.

  • 5 authors
·
Jun 7 2

CoCa: Contrastive Captioners are Image-Text Foundation Models

Exploring large-scale pretrained foundation models is of significant interest in computer vision because these models can be quickly transferred to many downstream tasks. This paper presents Contrastive Captioner (CoCa), a minimalist design to pretrain an image-text encoder-decoder foundation model jointly with contrastive loss and captioning loss, thereby subsuming model capabilities from contrastive approaches like CLIP and generative methods like SimVLM. In contrast to standard encoder-decoder transformers where all decoder layers attend to encoder outputs, CoCa omits cross-attention in the first half of decoder layers to encode unimodal text representations, and cascades the remaining decoder layers which cross-attend to the image encoder for multimodal image-text representations. We apply a contrastive loss between unimodal image and text embeddings, in addition to a captioning loss on the multimodal decoder outputs which predicts text tokens autoregressively. By sharing the same computational graph, the two training objectives are computed efficiently with minimal overhead. CoCa is pretrained end-to-end and from scratch on both web-scale alt-text data and annotated images by treating all labels simply as text, seamlessly unifying natural language supervision for representation learning. Empirically, CoCa achieves state-of-the-art performance with zero-shot transfer or minimal task-specific adaptation on a broad range of downstream tasks, spanning visual recognition (ImageNet, Kinetics-400/600/700, Moments-in-Time), crossmodal retrieval (MSCOCO, Flickr30K, MSR-VTT), multimodal understanding (VQA, SNLI-VE, NLVR2), and image captioning (MSCOCO, NoCaps). Notably on ImageNet classification, CoCa obtains 86.3% zero-shot top-1 accuracy, 90.6% with a frozen encoder and learned classification head, and new state-of-the-art 91.0% top-1 accuracy on ImageNet with a finetuned encoder.

  • 6 authors
·
May 4, 2022 1

Image-to-Video Transfer Learning based on Image-Language Foundation Models: A Comprehensive Survey

Image-Language Foundation Models (ILFM) have demonstrated remarkable success in image-text understanding/generation tasks, providing transferable multimodal representations that generalize across diverse downstream image-based tasks. The advancement of video-text research has spurred growing interest in extending image-based models to the video domain. This paradigm, known as image-to-video transfer learning, succeeds in alleviating the substantial data and computational requirements associated with training video-language foundation models from scratch for video-text learning. This survey provides the first comprehensive review of this emerging field, which begins by summarizing the widely used ILFM and their capabilities. We then systematically classify existing image-to-video transfer learning strategies into two categories: frozen features and modified features, depending on whether the original representations from ILFM are preserved or undergo modifications. Building upon the task-specific nature of image-to-video transfer, this survey methodically elaborates these strategies and details their applications across a spectrum of video-text learning tasks, ranging from fine-grained (e.g., spatio-temporal video grounding) to coarse-grained (e.g., video question answering). We further present a detailed experimental analysis to investigate the efficacy of different image-to-video transfer learning paradigms on a range of downstream video understanding tasks. Finally, we identify prevailing challenges and highlight promising directions for future research. By offering a comprehensive and structured overview, this survey aims to establish a structured roadmap for advancing video-text learning based on existing ILFM, and to inspire future research directions in this rapidly evolving domain.

  • 7 authors
·
Oct 12

Open-vocabulary Semantic Segmentation with Frozen Vision-Language Models

When trained at a sufficient scale, self-supervised learning has exhibited a notable ability to solve a wide range of visual or language understanding tasks. In this paper, we investigate simple, yet effective approaches for adapting the pre-trained foundation models to the downstream task of interest, namely, open-vocabulary semantic segmentation. To this end, we make the following contributions: (i) we introduce Fusioner, with a lightweight, transformer-based fusion module, that pairs the frozen visual representation with language concept through a handful of image segmentation data. As a consequence, the model gains the capability of zero-shot transfer to segment novel categories; (ii) without loss of generality, we experiment on a broad range of self-supervised models that have been pre-trained with different schemes, e.g. visual-only models (MoCo v3, DINO), language-only models (BERT), visual-language model (CLIP), and show that, the proposed fusion approach is effective to any pair of visual and language models, even those pre-trained on a corpus of uni-modal data; (iii) we conduct thorough ablation studies to analyze the critical components in our proposed Fusioner, while evaluating on standard benchmarks, e.g. PASCAL-5i and COCO-20i , it surpasses existing state-of-the-art models by a large margin, despite only being trained on frozen visual and language features; (iv) to measure the model's robustness on learning visual-language correspondence, we further evaluate on synthetic dataset, named Mosaic-4, where images are constructed by mosaicking the samples from FSS-1000. Fusioner demonstrates superior performance over previous models.

  • 5 authors
·
Oct 26, 2022

Escaping Plato's Cave: Towards the Alignment of 3D and Text Latent Spaces

Recent works have shown that, when trained at scale, uni-modal 2D vision and text encoders converge to learned features that share remarkable structural properties, despite arising from different representations. However, the role of 3D encoders with respect to other modalities remains unexplored. Furthermore, existing 3D foundation models that leverage large datasets are typically trained with explicit alignment objectives with respect to frozen encoders from other representations. In this work, we investigate the possibility of a posteriori alignment of representations obtained from uni-modal 3D encoders compared to text-based feature spaces. We show that naive post-training feature alignment of uni-modal text and 3D encoders results in limited performance. We then focus on extracting subspaces of the corresponding feature spaces and discover that by projecting learned representations onto well-chosen lower-dimensional subspaces the quality of alignment becomes significantly higher, leading to improved accuracy on matching and retrieval tasks. Our analysis further sheds light on the nature of these shared subspaces, which roughly separate between semantic and geometric data representations. Overall, ours is the first work that helps to establish a baseline for post-training alignment of 3D uni-modal and text feature spaces, and helps to highlight both the shared and unique properties of 3D data compared to other representations.

  • 8 authors
·
Mar 7 2

GameGen-X: Interactive Open-world Game Video Generation

We introduce GameGen-X, the first diffusion transformer model specifically designed for both generating and interactively controlling open-world game videos. This model facilitates high-quality, open-domain generation by simulating an extensive array of game engine features, such as innovative characters, dynamic environments, complex actions, and diverse events. Additionally, it provides interactive controllability, predicting and altering future content based on the current clip, thus allowing for gameplay simulation. To realize this vision, we first collected and built an Open-World Video Game Dataset from scratch. It is the first and largest dataset for open-world game video generation and control, which comprises over a million diverse gameplay video clips sampling from over 150 games with informative captions from GPT-4o. GameGen-X undergoes a two-stage training process, consisting of foundation model pre-training and instruction tuning. Firstly, the model was pre-trained via text-to-video generation and video continuation, endowing it with the capability for long-sequence, high-quality open-domain game video generation. Further, to achieve interactive controllability, we designed InstructNet to incorporate game-related multi-modal control signal experts. This allows the model to adjust latent representations based on user inputs, unifying character interaction and scene content control for the first time in video generation. During instruction tuning, only the InstructNet is updated while the pre-trained foundation model is frozen, enabling the integration of interactive controllability without loss of diversity and quality of generated video content.

  • 5 authors
·
Nov 1, 2024

Growing Transformers: Modular Composition and Layer-wise Expansion on a Frozen Substrate

The prevailing paradigm for scaling large language models (LLMs) involves monolithic, end-to-end training, a resource-intensive process that lacks flexibility. This paper explores an alternative, constructive approach to model development, built upon the foundation of non-trainable, deterministic input embeddings. In prior [1], we established that high-level semantic reasoning can emerge in Transformers using frozen embeddings derived from the visual structure of Unicode glyphs. Here, we demonstrate that this fixed representational substrate acts as a universal "docking port," enabling two powerful and efficient scaling paradigms: seamless modular composition and progressive layer-wise growth. First, we show that specialist models trained on disparate datasets (e.g., Russian and Chinese text) can be merged into a single, more capable Mixture-of-Experts (MoE) model, post-training, with zero architectural modification. This is achieved by simply averaging their output logits. The resulting MoE model exhibits immediate performance improvements on reasoning benchmarks like MMLU, surpassing its constituent experts without catastrophic forgetting. Second, we introduce a layer-wise constructive training methodology, where a deep Transformer is "grown" by progressively stacking and training one layer at a time. This method demonstrates stable convergence and a clear correlation between model depth and the emergence of complex reasoning abilities, such as those required for SQuAD. Our findings suggest a paradigm shift from monolithic optimization towards a more biological or constructive model of AI development, where complexity is built incrementally and modules can be composed freely. This opens new avenues for resource-efficient scaling, continual learning, and a more democratized ecosystem for building powerful AI systems. We release all code and models to facilitate further research.

  • 1 authors
·
Jul 8 2

Self-regulating Prompts: Foundational Model Adaptation without Forgetting

Prompt learning has emerged as an efficient alternative for fine-tuning foundational models, such as CLIP, for various downstream tasks. Conventionally trained using the task-specific objective, i.e., cross-entropy loss, prompts tend to overfit downstream data distributions and find it challenging to capture task-agnostic general features from the frozen CLIP. This leads to the loss of the model's original generalization capability. To address this issue, our work introduces a self-regularization framework for prompting called PromptSRC (Prompting with Self-regulating Constraints). PromptSRC guides the prompts to optimize for both task-specific and task-agnostic general representations using a three-pronged approach by: (a) regulating prompted representations via mutual agreement maximization with the frozen model, (b) regulating with self-ensemble of prompts over the training trajectory to encode their complementary strengths, and (c) regulating with textual diversity to mitigate sample diversity imbalance with the visual branch. To the best of our knowledge, this is the first regularization framework for prompt learning that avoids overfitting by jointly attending to pre-trained model features, the training trajectory during prompting, and the textual diversity. PromptSRC explicitly steers the prompts to learn a representation space that maximizes performance on downstream tasks without compromising CLIP generalization. We perform extensive experiments on 4 benchmarks where PromptSRC overall performs favorably well compared to the existing methods. Our code and pre-trained models are publicly available at: https://github.com/muzairkhattak/PromptSRC.

  • 6 authors
·
Jul 13, 2023

Uni3C: Unifying Precisely 3D-Enhanced Camera and Human Motion Controls for Video Generation

Camera and human motion controls have been extensively studied for video generation, but existing approaches typically address them separately, suffering from limited data with high-quality annotations for both aspects. To overcome this, we present Uni3C, a unified 3D-enhanced framework for precise control of both camera and human motion in video generation. Uni3C includes two key contributions. First, we propose a plug-and-play control module trained with a frozen video generative backbone, PCDController, which utilizes unprojected point clouds from monocular depth to achieve accurate camera control. By leveraging the strong 3D priors of point clouds and the powerful capacities of video foundational models, PCDController shows impressive generalization, performing well regardless of whether the inference backbone is frozen or fine-tuned. This flexibility enables different modules of Uni3C to be trained in specific domains, i.e., either camera control or human motion control, reducing the dependency on jointly annotated data. Second, we propose a jointly aligned 3D world guidance for the inference phase that seamlessly integrates both scenic point clouds and SMPL-X characters to unify the control signals for camera and human motion, respectively. Extensive experiments confirm that PCDController enjoys strong robustness in driving camera motion for fine-tuned backbones of video generation. Uni3C substantially outperforms competitors in both camera controllability and human motion quality. Additionally, we collect tailored validation sets featuring challenging camera movements and human actions to validate the effectiveness of our method.

  • 8 authors
·
Apr 21 2

Finetuning a Weather Foundation Model with Lightweight Decoders for Unseen Physical Processes

Recent advances in AI weather forecasting have led to the emergence of so-called "foundation models", typically defined by expensive pretraining and minimal fine-tuning for downstream tasks. However, in the natural sciences, a desirable foundation model should also encode meaningful statistical relationships between the underlying physical variables. This study evaluates the performance of the state-of-the-art Aurora foundation model in predicting hydrological variables, which were not considered during pretraining. We introduce a lightweight approach using shallow decoders trained on the latent representations of the pretrained model to predict these new variables. As a baseline, we compare this to fine-tuning the full model, which allows further optimization of the latent space while incorporating new variables into both inputs and outputs. The decoder-based approach requires 50% less training time and 35% less memory, while achieving strong accuracy across various hydrological variables and preserving desirable properties of the foundation model, such as autoregressive stability. Notably, decoder accuracy depends on the physical correlation between the new variables and those used during pretraining, indicating that Aurora's latent space captures meaningful physical relationships. In this sense, we argue that an important quality metric for foundation models in Earth sciences is their ability to be extended to new variables without a full fine-tuning. This provides a new perspective for making foundation models more accessible to communities with limited computational resources, while supporting broader adoption in Earth sciences.

  • 6 authors
·
Jun 23

On the Opportunities and Risks of Foundation Models

AI is undergoing a paradigm shift with the rise of models (e.g., BERT, DALL-E, GPT-3) that are trained on broad data at scale and are adaptable to a wide range of downstream tasks. We call these models foundation models to underscore their critically central yet incomplete character. This report provides a thorough account of the opportunities and risks of foundation models, ranging from their capabilities (e.g., language, vision, robotics, reasoning, human interaction) and technical principles(e.g., model architectures, training procedures, data, systems, security, evaluation, theory) to their applications (e.g., law, healthcare, education) and societal impact (e.g., inequity, misuse, economic and environmental impact, legal and ethical considerations). Though foundation models are based on standard deep learning and transfer learning, their scale results in new emergent capabilities,and their effectiveness across so many tasks incentivizes homogenization. Homogenization provides powerful leverage but demands caution, as the defects of the foundation model are inherited by all the adapted models downstream. Despite the impending widespread deployment of foundation models, we currently lack a clear understanding of how they work, when they fail, and what they are even capable of due to their emergent properties. To tackle these questions, we believe much of the critical research on foundation models will require deep interdisciplinary collaboration commensurate with their fundamentally sociotechnical nature.

  • 114 authors
·
Aug 16, 2021

Foundation Models for Scientific Discovery: From Paradigm Enhancement to Paradigm Transition

Foundation models (FMs), such as GPT-4 and AlphaFold, are reshaping the landscape of scientific research. Beyond accelerating tasks such as hypothesis generation, experimental design, and result interpretation, they prompt a more fundamental question: Are FMs merely enhancing existing scientific methodologies, or are they redefining the way science is conducted? In this paper, we argue that FMs are catalyzing a transition toward a new scientific paradigm. We introduce a three-stage framework to describe this evolution: (1) Meta-Scientific Integration, where FMs enhance workflows within traditional paradigms; (2) Hybrid Human-AI Co-Creation, where FMs become active collaborators in problem formulation, reasoning, and discovery; and (3) Autonomous Scientific Discovery, where FMs operate as independent agents capable of generating new scientific knowledge with minimal human intervention. Through this lens, we review current applications and emerging capabilities of FMs across existing scientific paradigms. We further identify risks and future directions for FM-enabled scientific discovery. This position paper aims to support the scientific community in understanding the transformative role of FMs and to foster reflection on the future of scientific discovery. Our project is available at https://github.com/usail-hkust/Awesome-Foundation-Models-for-Scientific-Discovery.

usail-hkust usail-hkust
·
Oct 16 4

Are Large Reasoning Models Interruptible?

Large Reasoning Models (LRMs) excel at complex reasoning but are traditionally evaluated in static, "frozen world" settings: model responses are assumed to be instantaneous, and the context of a request is presumed to be immutable over the duration of the response. While generally true for short-term tasks, the "frozen world" assumption breaks down in modern reasoning tasks such as assistive programming, where models may take hours to think through problems and code may change dramatically from the time the model starts thinking to the model's final output. In this work, we challenge the frozen world assumption and evaluate LRM robustness under two realistic dynamic scenarios: interruptions, which test the quality of the model's partial outputs on a limited budget, and dynamic context, which tests model adaptation to in-flight changes. Across mathematics and programming benchmarks that require long-form reasoning, static evaluations consistently overestimate robustness: even state-of-the-art LRMs, which achieve high accuracy in static settings, can fail unpredictably when interrupted or exposed to changing context, with performance dropping by up to 60% when updates are introduced late in the reasoning process. Our analysis further reveals several novel failure modes, including reasoning leakage, where models fold the reasoning into their final answer when interrupted; panic, where under time pressure models abandon reasoning entirely and return incorrect answers; and self-doubt, where performance degrades while incorporating updated information.

  • 6 authors
·
Oct 13 2

The Responsible Foundation Model Development Cheatsheet: A Review of Tools & Resources

Foundation model development attracts a rapidly expanding body of contributors, scientists, and applications. To help shape responsible development practices, we introduce the Foundation Model Development Cheatsheet: a growing collection of 250+ tools and resources spanning text, vision, and speech modalities. We draw on a large body of prior work to survey resources (e.g. software, documentation, frameworks, guides, and practical tools) that support informed data selection, processing, and understanding, precise and limitation-aware artifact documentation, efficient model training, advance awareness of the environmental impact from training, careful model evaluation of capabilities, risks, and claims, as well as responsible model release, licensing and deployment practices. We hope this curated collection of resources helps guide more responsible development. The process of curating this list, enabled us to review the AI development ecosystem, revealing what tools are critically missing, misused, or over-used in existing practices. We find that (i) tools for data sourcing, model evaluation, and monitoring are critically under-serving ethical and real-world needs, (ii) evaluations for model safety, capabilities, and environmental impact all lack reproducibility and transparency, (iii) text and particularly English-centric analyses continue to dominate over multilingual and multi-modal analyses, and (iv) evaluation of systems, rather than just models, is needed so that capabilities and impact are assessed in context.

  • 23 authors
·
Jun 24, 2024

One Initialization to Rule them All: Fine-tuning via Explained Variance Adaptation

Foundation models (FMs) are pre-trained on large-scale datasets and then fine-tuned on a downstream task for a specific application. The most successful and most commonly used fine-tuning method is to update the pre-trained weights via a low-rank adaptation (LoRA). LoRA introduces new weight matrices that are usually initialized at random with a uniform rank distribution across model weights. Recent works focus on weight-driven initialization or learning of adaptive ranks during training. Both approaches have only been investigated in isolation, resulting in slow convergence or a uniform rank distribution, in turn leading to sub-optimal performance. We propose to enhance LoRA by initializing the new weights in a data-driven manner by computing singular value decomposition on minibatches of activation vectors. Then, we initialize the LoRA matrices with the obtained right-singular vectors and re-distribute ranks among all weight matrices to explain the maximal amount of variance and continue the standard LoRA fine-tuning procedure. This results in our new method Explained Variance Adaptation (EVA). We apply EVA to a variety of fine-tuning tasks ranging from language generation and understanding to image classification and reinforcement learning. EVA exhibits faster convergence than competitors and attains the highest average score across a multitude of tasks per domain.

  • 6 authors
·
Oct 9, 2024 2

Learning Embeddings with Centroid Triplet Loss for Object Identification in Robotic Grasping

Foundation models are a strong trend in deep learning and computer vision. These models serve as a base for applications as they require minor or no further fine-tuning by developers to integrate into their applications. Foundation models for zero-shot object segmentation such as Segment Anything (SAM) output segmentation masks from images without any further object information. When they are followed in a pipeline by an object identification model, they can perform object detection without training. Here, we focus on training such an object identification model. A crucial practical aspect for an object identification model is to be flexible in input size. As object identification is an image retrieval problem, a suitable method should handle multi-query multi-gallery situations without constraining the number of input images (e.g. by having fixed-size aggregation layers). The key solution to train such a model is the centroid triplet loss (CTL), which aggregates image features to their centroids. CTL yields high accuracy, avoids misleading training signals and keeps the model input size flexible. In our experiments, we establish a new state of the art on the ArmBench object identification task, which shows general applicability of our model. We furthermore demonstrate an integrated unseen object detection pipeline on the challenging HOPE dataset, which requires fine-grained detection. There, our pipeline matches and surpasses related methods which have been trained on dataset-specific data.

  • 5 authors
·
Apr 9, 2024

Towards a Physics Foundation Model

Foundation models have revolutionized natural language processing through a ``train once, deploy anywhere'' paradigm, where a single pre-trained model adapts to countless downstream tasks without retraining. Access to a Physics Foundation Model (PFM) would be transformative -- democratizing access to high-fidelity simulations, accelerating scientific discovery, and eliminating the need for specialized solver development. Yet current physics-aware machine learning approaches remain fundamentally limited to single, narrow domains and require retraining for each new system. We present the General Physics Transformer (GPhyT), trained on 1.8 TB of diverse simulation data, that demonstrates foundation model capabilities are achievable for physics. Our key insight is that transformers can learn to infer governing dynamics from context, enabling a single model to simulate fluid-solid interactions, shock waves, thermal convection, and multi-phase dynamics without being told the underlying equations. GPhyT achieves three critical breakthroughs: (1) superior performance across multiple physics domains, outperforming specialized architectures by up to 29x, (2) zero-shot generalization to entirely unseen physical systems through in-context learning, and (3) stable long-term predictions through 50-timestep rollouts. By establishing that a single model can learn generalizable physical principles from data alone, this work opens the path toward a universal PFM that could transform computational science and engineering.

  • 3 authors
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Sep 17 2

GraphFM: A Comprehensive Benchmark for Graph Foundation Model

Foundation Models (FMs) serve as a general class for the development of artificial intelligence systems, offering broad potential for generalization across a spectrum of downstream tasks. Despite extensive research into self-supervised learning as the cornerstone of FMs, several outstanding issues persist in Graph Foundation Models that rely on graph self-supervised learning, namely: 1) Homogenization. The extent of generalization capability on downstream tasks remains unclear. 2) Scalability. It is unknown how effectively these models can scale to large datasets. 3) Efficiency. The training time and memory usage of these models require evaluation. 4) Training Stop Criteria. Determining the optimal stopping strategy for pre-training across multiple tasks to maximize performance on downstream tasks. To address these questions, we have constructed a rigorous benchmark that thoroughly analyzes and studies the generalization and scalability of self-supervised Graph Neural Network (GNN) models. Regarding generalization, we have implemented and compared the performance of various self-supervised GNN models, trained to generate node representations, across tasks such as node classification, link prediction, and node clustering. For scalability, we have compared the performance of various models after training using full-batch and mini-batch strategies. Additionally, we have assessed the training efficiency of these models by conducting experiments to test their GPU memory usage and throughput. Through these experiments, we aim to provide insights to motivate future research. The code for this benchmark is publicly available at https://github.com/NYUSHCS/GraphFM.

  • 7 authors
·
Jun 12, 2024

Foundation Models for Decision Making: Problems, Methods, and Opportunities

Foundation models pretrained on diverse data at scale have demonstrated extraordinary capabilities in a wide range of vision and language tasks. When such models are deployed in real world environments, they inevitably interface with other entities and agents. For example, language models are often used to interact with human beings through dialogue, and visual perception models are used to autonomously navigate neighborhood streets. In response to these developments, new paradigms are emerging for training foundation models to interact with other agents and perform long-term reasoning. These paradigms leverage the existence of ever-larger datasets curated for multimodal, multitask, and generalist interaction. Research at the intersection of foundation models and decision making holds tremendous promise for creating powerful new systems that can interact effectively across a diverse range of applications such as dialogue, autonomous driving, healthcare, education, and robotics. In this manuscript, we examine the scope of foundation models for decision making, and provide conceptual tools and technical background for understanding the problem space and exploring new research directions. We review recent approaches that ground foundation models in practical decision making applications through a variety of methods such as prompting, conditional generative modeling, planning, optimal control, and reinforcement learning, and discuss common challenges and open problems in the field.

  • 6 authors
·
Mar 7, 2023

SatVision-TOA: A Geospatial Foundation Model for Coarse-Resolution All-Sky Remote Sensing Imagery

Foundation models have the potential to transform the landscape of remote sensing (RS) data analysis by enabling large computer vision models to be pre-trained on vast amounts of remote sensing data. These models can then be fine-tuned with small amounts of labeled training and applied to a variety of applications. Most existing foundation models are designed for high spatial resolution, cloud-free satellite imagery or photos, limiting their applicability in scenarios that require frequent temporal monitoring or broad spectral profiles. As a result, foundation models trained solely on cloud-free images have limited utility for applications that involve atmospheric variables or require atmospheric corrections. We introduce SatVision-TOA, a novel foundation model pre-trained on 14-band MODIS L1B Top-Of-Atmosphere (TOA) radiance imagery, addressing the need for models pre-trained to handle moderate- and coarse-resolution all-sky remote sensing data. The SatVision-TOA model is pre-trained using a Masked-Image-Modeling (MIM) framework and the SwinV2 architecture, and learns detailed contextual representations through self-supervised learning without the need for labels. It is a 3 billion parameter model that is trained on 100 million images. To our knowledge this is the largest foundation model trained solely on satellite RS imagery. Results show that SatVision-TOA achieves superior performance over baseline methods on downstream tasks such as 3D cloud retrieval. Notably, the model achieves a mean intersection over union (mIOU) of 0.46, a substantial improvement over the baseline mIOU of 0.22. Additionally, the rate of false negative results in the fine-tuning task were reduced by over 50% compared to the baseline. Our work advances pre-trained vision modeling for multispectral RS by learning from a variety of atmospheric and aerosol conditions to improve cloud and land surface monitoring.

  • 6 authors
·
Nov 25, 2024

EoS-FM: Can an Ensemble of Specialist Models act as a Generalist Feature Extractor?

Recent advances in foundation models have shown great promise in domains such as natural language processing and computer vision, and similar efforts are now emerging in the Earth Observation community. These models aim to generalize across tasks with limited supervision, reducing the need for training separate models for each task. However, current strategies, which largely focus on scaling model size and dataset volume, require prohibitive computational and data resources, limiting accessibility to only a few large institutions. Moreover, this paradigm of ever-larger models stands in stark contrast with the principles of sustainable and environmentally responsible AI, as it leads to immense carbon footprints and resource inefficiency. In this work, we present a novel and efficient alternative: an Ensemble-of-Specialists framework for building Remote Sensing Foundation Models (RSFMs). Our method decomposes the training process into lightweight, task-specific ConvNeXtV2 specialists that can be frozen and reused. This modular approach offers strong advantages in efficiency, interpretability, and extensibility. Moreover, it naturally supports federated training, pruning, and continuous specialist integration, making it particularly well-suited for collaborative and resource-constrained settings. Our framework sets a new direction for building scalable and efficient RSFMs. All codes and pretrained models are available at https://github.com/pierreadorni/EoS-FM.

  • 4 authors
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Nov 26

A Method for Identifying Farmland System Habitat Types Based on the Dynamic-Weighted Feature Fusion Network Model

Addressing the current lack of a standardized habitat classification system for cultivated land ecosystems, incomplete coverage of habitat types, and the inability of existing models to effectively integrate semantic and texture features-resulting in insufficient segmentation accuracy and blurred boundaries for multi-scale habitats (e.g., large-scale field plots and micro-habitats)-this study developed a comprehensively annotated ultra-high-resolution remote sensing image dataset encompassing 15 categories of cultivated land system habitats. Furthermore, we propose a Dynamic-Weighted Feature Fusion Network (DWFF-Net). The encoder of this model utilizes a frozen-parameter DINOv3 to extract foundational features. By analyzing the relationships between different category images and feature maps, we introduce a data-level adaptive dynamic weighting strategy for feature fusion. The decoder incorporates a dynamic weight computation network to achieve thorough integration of multi-layer features, and a hybrid loss function is adopted to optimize model training. Experimental results on the constructed dataset demonstrate that the proposed model achieves a mean Intersection over Union (mIoU) of 0.6979 and an F1-score of 0.8049, outperforming the baseline network by 0.021 and 0.0161, respectively. Ablation studies further confirm the complementary nature of multi-layer feature fusion, which effectively improves the IoU for micro-habitat categories such as field ridges. This study establishes a habitat identification framework for cultivated land systems based on adaptive multi-layer feature fusion, enabling sub-meter precision habitat mapping at a low cost and providing robust technical support for fine-grained habitat monitoring in cultivated landscapes.

  • 5 authors
·
Nov 10

FlowState: Sampling Rate Invariant Time Series Forecasting

Foundation models (FMs) have transformed natural language processing, but their success has not yet translated to time series forecasting. Existing time series foundation models (TSFMs), often based on transformer variants, struggle with generalization across varying context and target lengths, lack adaptability to different sampling rates, and are computationally inefficient. We introduce FlowState, a novel TSFM architecture that addresses these challenges through two key innovations: a state space model (SSM) based encoder and a functional basis decoder. This design enables continuous-time modeling and dynamic time-scale adjustment, allowing FlowState to inherently generalize across all possible temporal resolutions, and dynamically adjust the forecasting horizons. In contrast to other state-of-the-art TSFMs, which require training data across all possible sampling rates to memorize patterns at each scale, FlowState inherently adapts its internal dynamics to the input scale, enabling smaller models, reduced data requirements, and improved efficiency. We further propose an efficient pretraining strategy that improves robustness and accelerates training. Despite being the smallest model, FlowState outperforms all other models and is state-of-the-art for the GIFT-ZS and the Chronos-ZS benchmarks. Ablation studies confirm the effectiveness of its components, and we demonstrate its unique ability to adapt online to varying input sampling rates.

  • 4 authors
·
Aug 7

Foundation Models for Natural Language Processing -- Pre-trained Language Models Integrating Media

This open access book provides a comprehensive overview of the state of the art in research and applications of Foundation Models and is intended for readers familiar with basic Natural Language Processing (NLP) concepts. Over the recent years, a revolutionary new paradigm has been developed for training models for NLP. These models are first pre-trained on large collections of text documents to acquire general syntactic knowledge and semantic information. Then, they are fine-tuned for specific tasks, which they can often solve with superhuman accuracy. When the models are large enough, they can be instructed by prompts to solve new tasks without any fine-tuning. Moreover, they can be applied to a wide range of different media and problem domains, ranging from image and video processing to robot control learning. Because they provide a blueprint for solving many tasks in artificial intelligence, they have been called Foundation Models. After a brief introduction to basic NLP models the main pre-trained language models BERT, GPT and sequence-to-sequence transformer are described, as well as the concepts of self-attention and context-sensitive embedding. Then, different approaches to improving these models are discussed, such as expanding the pre-training criteria, increasing the length of input texts, or including extra knowledge. An overview of the best-performing models for about twenty application areas is then presented, e.g., question answering, translation, story generation, dialog systems, generating images from text, etc. For each application area, the strengths and weaknesses of current models are discussed, and an outlook on further developments is given. In addition, links are provided to freely available program code. A concluding chapter summarizes the economic opportunities, mitigation of risks, and potential developments of AI.

  • 2 authors
·
Feb 16, 2023

Robot-Powered Data Flywheels: Deploying Robots in the Wild for Continual Data Collection and Foundation Model Adaptation

Foundation models (FM) have unlocked powerful zero-shot capabilities in vision and language, yet their reliance on internet pretraining data leaves them brittle in unstructured, real-world settings. The messy, real-world data encountered during deployment (e.g. occluded or multilingual text) remains massively underrepresented in existing corpora. Robots, as embodied agents, are uniquely positioned to close this gap: they can act in physical environments to collect large-scale, real-world data that enriches FM training with precisely the examples current models lack. We introduce the Robot-Powered Data Flywheel, a framework that transforms robots from FM consumers into data generators. By deploying robots equipped with FMs in the wild, we enable a virtuous cycle: robots perform useful tasks while collecting real-world data that improves both domain-specific adaptation and domain-adjacent generalization. We instantiate this framework with Scanford, a mobile manipulator deployed in the East Asia Library for 2 weeks. Scanford autonomously scans shelves, identifies books using a vision-language model (VLM), and leverages the library catalog to label images without human annotation. This deployment both aids librarians and produces a dataset to finetune the underlying VLM, improving performance on the domain-specific in-the-wild library setting and on domain-adjacent multilingual OCR benchmarks. Using data collected from 2103 shelves, Scanford improves VLM performance on book identification from 32.0% to 71.8% and boosts domain-adjacent multilingual OCR from 24.8% to 46.6% (English) and 30.8% to 38.0% (Chinese), while saving an ~18.7 hrs of human time. These results highlight how robot-powered data flywheels can both reduce human effort in real deployments and unlock new pathways for continually adapting FMs to the messiness of reality. More details are at: https://scanford-robot.github.io

  • 7 authors
·
Nov 24

Foundation Models for Generalist Geospatial Artificial Intelligence

Significant progress in the development of highly adaptable and reusable Artificial Intelligence (AI) models is expected to have a significant impact on Earth science and remote sensing. Foundation models are pre-trained on large unlabeled datasets through self-supervision, and then fine-tuned for various downstream tasks with small labeled datasets. This paper introduces a first-of-a-kind framework for the efficient pre-training and fine-tuning of foundational models on extensive geospatial data. We have utilized this framework to create Prithvi, a transformer-based geospatial foundational model pre-trained on more than 1TB of multispectral satellite imagery from the Harmonized Landsat-Sentinel 2 (HLS) dataset. Our study demonstrates the efficacy of our framework in successfully fine-tuning Prithvi to a range of Earth observation tasks that have not been tackled by previous work on foundation models involving multi-temporal cloud gap imputation, flood mapping, wildfire scar segmentation, and multi-temporal crop segmentation. Our experiments show that the pre-trained model accelerates the fine-tuning process compared to leveraging randomly initialized weights. In addition, pre-trained Prithvi compares well against the state-of-the-art, e.g., outperforming a conditional GAN model in multi-temporal cloud imputation by up to 5pp (or 5.7%) in the structural similarity index. Finally, due to the limited availability of labeled data in the field of Earth observation, we gradually reduce the quantity of available labeled data for refining the model to evaluate data efficiency and demonstrate that data can be decreased significantly without affecting the model's accuracy. The pre-trained 100 million parameter model and corresponding fine-tuning workflows have been released publicly as open source contributions to the global Earth sciences community through Hugging Face.

  • 33 authors
·
Oct 28, 2023

Integrating Reinforcement Learning with Foundation Models for Autonomous Robotics: Methods and Perspectives

Foundation models (FMs), large deep learning models pre-trained on vast, unlabeled datasets, exhibit powerful capabilities in understanding complex patterns and generating sophisticated outputs. However, they often struggle to adapt to specific tasks. Reinforcement learning (RL), which allows agents to learn through interaction and feedback, offers a compelling solution. Integrating RL with FMs enables these models to achieve desired outcomes and excel at particular tasks. Additionally, RL can be enhanced by leveraging the reasoning and generalization capabilities of FMs. This synergy is revolutionizing various fields, including robotics. FMs, rich in knowledge and generalization, provide robots with valuable information, while RL facilitates learning and adaptation through real-world interactions. This survey paper comprehensively explores this exciting intersection, examining how these paradigms can be integrated to advance robotic intelligence. We analyze the use of foundation models as action planners, the development of robotics-specific foundation models, and the mutual benefits of combining FMs with RL. Furthermore, we present a taxonomy of integration approaches, including large language models, vision-language models, diffusion models, and transformer-based RL models. We also explore how RL can utilize world representations learned from FMs to enhance robotic task execution. Our survey aims to synthesize current research and highlight key challenges in robotic reasoning and control, particularly in the context of integrating FMs and RL--two rapidly evolving technologies. By doing so, we seek to spark future research and emphasize critical areas that require further investigation to enhance robotics. We provide an updated collection of papers based on our taxonomy, accessible on our open-source project website at: https://github.com/clmoro/Robotics-RL-FMs-Integration.

  • 8 authors
·
Oct 21, 2024

Prithvi WxC: Foundation Model for Weather and Climate

Triggered by the realization that AI emulators can rival the performance of traditional numerical weather prediction models running on HPC systems, there is now an increasing number of large AI models that address use cases such as forecasting, downscaling, or nowcasting. While the parallel developments in the AI literature focus on foundation models -- models that can be effectively tuned to address multiple, different use cases -- the developments on the weather and climate side largely focus on single-use cases with particular emphasis on mid-range forecasting. We close this gap by introducing Prithvi WxC, a 2.3 billion parameter foundation model developed using 160 variables from the Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2). Prithvi WxC employs an encoder-decoder-based architecture, incorporating concepts from various recent transformer models to effectively capture both regional and global dependencies in the input data. The model has been designed to accommodate large token counts to model weather phenomena in different topologies at fine resolutions. Furthermore, it is trained with a mixed objective that combines the paradigms of masked reconstruction with forecasting. We test the model on a set of challenging downstream tasks namely: Autoregressive rollout forecasting, Downscaling, Gravity wave flux parameterization, and Extreme events estimation. The pretrained model with 2.3 billion parameters, along with the associated fine-tuning workflows, has been publicly released as an open-source contribution via Hugging Face.

  • 29 authors
·
Sep 20, 2024 4

Bootstrapping World Models from Dynamics Models in Multimodal Foundation Models

To what extent do vision-and-language foundation models possess a realistic world model (observation times action rightarrow observation) and a dynamics model (observation times observation rightarrow action), when actions are expressed through language? While open-source foundation models struggle with both, we find that fine-tuning them to acquire a dynamics model through supervision is significantly easier than acquiring a world model. In turn, dynamics models can be used to bootstrap world models through two main strategies: 1) weakly supervised learning from synthetic data and 2) inference time verification. Firstly, the dynamics model can annotate actions for unlabelled pairs of video frame observations to expand the training data. We further propose a new objective, where image tokens in observation pairs are weighted by their importance, as predicted by a recognition model. Secondly, the dynamics models can assign rewards to multiple samples of the world model to score them, effectively guiding search at inference time. We evaluate the world models resulting from both strategies through the task of action-centric image editing on Aurora-Bench. Our best model achieves a performance competitive with state-of-the-art image editing models, improving on them by a margin of 15% on real-world subsets according to GPT4o-as-judge, and achieving the best average human evaluation across all subsets of Aurora-Bench.

  • 5 authors
·
Jun 6 2

A Graph Neural Network for the Era of Large Atomistic Models

Foundation models, or large atomistic models (LAMs), aim to universally represent the ground-state potential energy surface (PES) of atomistic systems as defined by density functional theory (DFT). The scaling law is pivotal in the development of large models, suggesting that their generalizability in downstream tasks consistently improves with increased model size, expanded training datasets, and larger computational budgets. In this study, we present DPA3, a multi-layer graph neural network founded on line graph series (LiGS), designed explicitly for the era of LAMs. We demonstrate that the generalization error of the DPA3 model adheres to the scaling law. The scalability in the number of model parameters is attained by stacking additional layers within DPA3. Additionally, the model employs a dataset encoding mechanism that decouples the scaling of training data size from the model size within its multi-task training framework. When trained as problem-oriented potential energy models, the DPA3 model exhibits superior accuracy in the majority of benchmark cases, encompassing systems with diverse features, including molecules, bulk materials, surface and cluster catalysts, two-dimensional materials, and battery materials. When trained as a LAM on the OpenLAM-v1 dataset, the DPA-3.1-3M model exhibits state-of-the-art performance in the LAMBench benchmark suite for LAMs, demonstrating lowest overall zero-shot generalization error across 17 downstream tasks from a broad spectrum of research domains. This performance suggests superior accuracy as an out-of-the-box potential model, requiring minimal fine-tuning data for downstream scientific applications.

  • 14 authors
·
Jun 2

Foundation Models in Robotics: Applications, Challenges, and the Future

We survey applications of pretrained foundation models in robotics. Traditional deep learning models in robotics are trained on small datasets tailored for specific tasks, which limits their adaptability across diverse applications. In contrast, foundation models pretrained on internet-scale data appear to have superior generalization capabilities, and in some instances display an emergent ability to find zero-shot solutions to problems that are not present in the training data. Foundation models may hold the potential to enhance various components of the robot autonomy stack, from perception to decision-making and control. For example, large language models can generate code or provide common sense reasoning, while vision-language models enable open-vocabulary visual recognition. However, significant open research challenges remain, particularly around the scarcity of robot-relevant training data, safety guarantees and uncertainty quantification, and real-time execution. In this survey, we study recent papers that have used or built foundation models to solve robotics problems. We explore how foundation models contribute to improving robot capabilities in the domains of perception, decision-making, and control. We discuss the challenges hindering the adoption of foundation models in robot autonomy and provide opportunities and potential pathways for future advancements. The GitHub project corresponding to this paper (Preliminary release. We are committed to further enhancing and updating this work to ensure its quality and relevance) can be found here: https://github.com/robotics-survey/Awesome-Robotics-Foundation-Models

  • 15 authors
·
Dec 12, 2023

On Creating a Causally Grounded Usable Rating Method for Assessing the Robustness of Foundation Models Supporting Time Series

Foundation Models (FMs) have improved time series forecasting in various sectors, such as finance, but their vulnerability to input disturbances can hinder their adoption by stakeholders, such as investors and analysts. To address this, we propose a causally grounded rating framework to study the robustness of Foundational Models for Time Series (FMTS) with respect to input perturbations. We evaluate our approach to the stock price prediction problem, a well-studied problem with easily accessible public data, evaluating six state-of-the-art (some multi-modal) FMTS across six prominent stocks spanning three industries. The ratings proposed by our framework effectively assess the robustness of FMTS and also offer actionable insights for model selection and deployment. Within the scope of our study, we find that (1) multi-modal FMTS exhibit better robustness and accuracy compared to their uni-modal versions and, (2) FMTS pre-trained on time series forecasting task exhibit better robustness and forecasting accuracy compared to general-purpose FMTS pre-trained across diverse settings. Further, to validate our framework's usability, we conduct a user study showcasing FMTS prediction errors along with our computed ratings. The study confirmed that our ratings reduced the difficulty for users in comparing the robustness of different systems.

  • 8 authors
·
Feb 17

On the Workflows and Smells of Leaderboard Operations (LBOps): An Exploratory Study of Foundation Model Leaderboards

Foundation models (FM), such as large language models (LLMs), which are large-scale machine learning (ML) models, have demonstrated remarkable adaptability in various downstream software engineering (SE) tasks, such as code completion, code understanding, and software development. As a result, FM leaderboards, especially those hosted on cloud platforms, have become essential tools for SE teams to compare and select the best third-party FMs for their specific products and purposes. However, the lack of standardized guidelines for FM evaluation and comparison threatens the transparency of FM leaderboards and limits stakeholders' ability to perform effective FM selection. As a first step towards addressing this challenge, our research focuses on understanding how these FM leaderboards operate in real-world scenarios ("leaderboard operations") and identifying potential leaderboard pitfalls and areas for improvement ("leaderboard smells"). In this regard, we perform a multivocal literature review to collect up to 721 FM leaderboards, after which we examine their documentation and engage in direct communication with leaderboard operators to understand their workflow patterns. Using card sorting and negotiated agreement, we identify 5 unique workflow patterns and develop a domain model that outlines the essential components and their interaction within FM leaderboards. We then identify 8 unique types of leaderboard smells in LBOps. By mitigating these smells, SE teams can improve transparency, accountability, and collaboration in current LBOps practices, fostering a more robust and responsible ecosystem for FM comparison and selection.

  • 5 authors
·
Jul 4, 2024

VISTA3D: A Unified Segmentation Foundation Model For 3D Medical Imaging

Foundation models for interactive segmentation in 2D natural images and videos have sparked significant interest in building 3D foundation models for medical imaging. However, the domain gaps and clinical use cases for 3D medical imaging require a dedicated model that diverges from existing 2D solutions. Specifically, such foundation models should support a full workflow that can actually reduce human effort. Treating 3D medical images as sequences of 2D slices and reusing interactive 2D foundation models seems straightforward, but 2D annotation is too time-consuming for 3D tasks. Moreover, for large cohort analysis, it's the highly accurate automatic segmentation models that reduce the most human effort. However, these models lack support for interactive corrections and lack zero-shot ability for novel structures, which is a key feature of "foundation". While reusing pre-trained 2D backbones in 3D enhances zero-shot potential, their performance on complex 3D structures still lags behind leading 3D models. To address these issues, we present VISTA3D, Versatile Imaging SegmenTation and Annotation model, that targets to solve all these challenges and requirements with one unified foundation model. VISTA3D is built on top of the well-established 3D segmentation pipeline, and it is the first model to achieve state-of-the-art performance in both 3D automatic (supporting 127 classes) and 3D interactive segmentation, even when compared with top 3D expert models on large and diverse benchmarks. Additionally, VISTA3D's 3D interactive design allows efficient human correction, and a novel 3D supervoxel method that distills 2D pretrained backbones grants VISTA3D top 3D zero-shot performance. We believe the model, recipe, and insights represent a promising step towards a clinically useful 3D foundation model. Code and weights are publicly available at https://github.com/Project-MONAI/VISTA.

  • 14 authors
·
Jun 7, 2024

Model Context Protocol (MCP) at First Glance: Studying the Security and Maintainability of MCP Servers

Although Foundation Models (FMs), such as GPT-4, are increasingly used in domains like finance and software engineering, reliance on textual interfaces limits these models' real-world interaction. To address this, FM providers introduced tool calling-triggering a proliferation of frameworks with distinct tool interfaces. In late 2024, Anthropic introduced the Model Context Protocol (MCP) to standardize this tool ecosystem, which has become the de facto standard with over eight million weekly SDK downloads. Despite its adoption, MCP's AI-driven, non-deterministic control flow introduces new risks to sustainability, security, and maintainability, warranting closer examination. Towards this end, we present the first large-scale empirical study of MCP servers. Using state-of-the-art health metrics and a hybrid analysis pipeline, combining a general-purpose static analysis tool with an MCP-specific scanner, we evaluate 1,899 open-source MCP servers to assess their health, security, and maintainability. Despite MCP servers demonstrating strong health metrics, we identify eight distinct vulnerabilities - only three overlapping with traditional software vulnerabilities. Additionally, 7.2% of servers contain general vulnerabilities and 5.5% exhibit MCP-specific tool poisoning. Regarding maintainability, while 66% exhibit code smells, 14.4% contain nine bug patterns overlapping with traditional open-source software projects. These findings highlight the need for MCP-specific vulnerability detection techniques while reaffirming the value of traditional analysis and refactoring practices.

  • 6 authors
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Jun 16

Towards Responsible AI in the Era of ChatGPT: A Reference Architecture for Designing Foundation Model-based AI Systems

The release of ChatGPT, Bard, and other large language model (LLM)-based chatbots has drawn huge attention on foundations models worldwide. There is a growing trend that foundation models will serve as the fundamental building blocks for most of the future AI systems. However, incorporating foundation models in AI systems raises significant concerns about responsible AI due to their black box nature and rapidly advancing super-intelligence. Additionally, the foundation model's growing capabilities can eventually absorb the other components of AI systems, introducing the moving boundary and interface evolution challenges in architecture design. To address these challenges, this paper proposes a pattern-oriented responsible-AI-by-design reference architecture for designing foundation model-based AI systems. Specially, the paper first presents an architecture evolution of AI systems in the era of foundation models, from "foundation-model-as-a-connector" to "foundation-model-as-a-monolithic architecture". The paper then identifies the key design decision points and proposes a pattern-oriented reference architecture to provide reusable responsible-AI-by-design architectural solutions to address the new architecture evolution and responsible AI challenges. The patterns can be embedded as product features of foundation model-based AI systems and can enable organisations to capitalise on the potential of foundation models while minimising associated risks.

  • 5 authors
·
Apr 13, 2023

Chain-of-Agents: End-to-End Agent Foundation Models via Multi-Agent Distillation and Agentic RL

Recent advances in large language models (LLMs) and multi-agent systems have demonstrated remarkable capabilities in complex problem-solving tasks such as deep research, vibe coding, and mathematical reasoning. However, most existing multi-agent systems are built upon manual prompt/workflow engineering with sophisticated agent frameworks, making them computationally inefficient, less capable, and can not benefit from data-centric learning. In this work, we introduce Chain-of-Agents (CoA), a novel paradigm of LLM reasoning that enables native end-to-end complex problem-solving in the same way as a multi-agent system (i.e., multi-turn problem solving with multiple tools and multiple agents) within one model. In chain-of-agents problem-solving, the model dynamically activates different tool agents and role-playing agents to simulate multi-agent collaboration in an end-to-end fashion. To elicit end-to-end chain-of-agents problem-solving abilities in LLMs, we introduce a multi-agent distillation framework to distill state-of-the-art multi-agent systems into chain-of-agents trajectories for agentic supervised fine-tuning. We then use agentic reinforcement learning on verifiable agentic tasks to further improve the models' capabilities on chain-of-agents problem solving. We call the resulting models Agent Foundation Models (AFMs). Our empirical studies demonstrate that AFM establishes new state-of-the-art performance across diverse benchmarks in both web agent and code agent settings. We make the entire research, including the model weights, code for training and evaluation, and the training data, fully open-sourced, which offers a solid starting point for future research on agent models and agentic RL.

Foundation Model Driven Robotics: A Comprehensive Review

The rapid emergence of foundation models, particularly Large Language Models (LLMs) and Vision-Language Models (VLMs), has introduced a transformative paradigm in robotics. These models offer powerful capabilities in semantic understanding, high-level reasoning, and cross-modal generalization, enabling significant advances in perception, planning, control, and human-robot interaction. This critical review provides a structured synthesis of recent developments, categorizing applications across simulation-driven design, open-world execution, sim-to-real transfer, and adaptable robotics. Unlike existing surveys that emphasize isolated capabilities, this work highlights integrated, system-level strategies and evaluates their practical feasibility in real-world environments. Key enabling trends such as procedural scene generation, policy generalization, and multimodal reasoning are discussed alongside core bottlenecks, including limited embodiment, lack of multimodal data, safety risks, and computational constraints. Through this lens, this paper identifies both the architectural strengths and critical limitations of foundation model-based robotics, highlighting open challenges in real-time operation, grounding, resilience, and trust. The review concludes with a roadmap for future research aimed at bridging semantic reasoning and physical intelligence through more robust, interpretable, and embodied models.

  • 2 authors
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Jul 14

Model Breadcrumbs: Scaling Multi-Task Model Merging with Sparse Masks

The rapid development of AI systems has been greatly influenced by the emergence of foundation models. A common approach for targeted problems involves fine-tuning these pre-trained foundation models for specific target tasks, resulting in a rapid spread of models fine-tuned across a diverse array of tasks. This work focuses on the problem of merging multiple fine-tunings of the same foundation model derived from a spectrum of auxiliary tasks. We introduce a new simple method, Model Breadcrumbs, which consists of a sparsely defined set of weights that carve out a trajectory within the weight space of a pre-trained model, enhancing task performance when traversed. These breadcrumbs are constructed by subtracting the weights from a pre-trained model before and after fine-tuning, followed by a sparsification process that eliminates weight outliers and negligible perturbations. Our experiments demonstrate the effectiveness of Model Breadcrumbs to simultaneously improve performance across multiple tasks. This contribution aligns with the evolving paradigm of updatable machine learning, reminiscent of the collaborative principles underlying open-source software development, fostering a community-driven effort to reliably update machine learning models. Our method is shown to be more efficient and unlike previous proposals does not require hyperparameter tuning for each new task added. Through extensive experimentation involving various models, tasks, and modalities we establish that integrating Model Breadcrumbs offers a simple, efficient, and highly effective approach for constructing multi-task models and facilitating updates to foundation models.

  • 2 authors
·
Dec 11, 2023

Robot Learning in the Era of Foundation Models: A Survey

The proliferation of Large Language Models (LLMs) has s fueled a shift in robot learning from automation towards general embodied Artificial Intelligence (AI). Adopting foundation models together with traditional learning methods to robot learning has increasingly gained recent interest research community and showed potential for real-life application. However, there are few literatures comprehensively reviewing the relatively new technologies combined with robotics. The purpose of this review is to systematically assess the state-of-the-art foundation model techniques in the robot learning and to identify future potential areas. Specifically, we first summarized the technical evolution of robot learning and identified the necessary preliminary preparations for foundation models including the simulators, datasets, foundation model framework. In addition, we focused on the following four mainstream areas of robot learning including manipulation, navigation, planning, and reasoning and demonstrated how the foundation model techniques can be adopted in the above scenarios. Furthermore, critical issues which are neglected in the current literatures including robot hardware and software decoupling, dynamic data, generalization performance with the presence of human, etc. were discussed. This review highlights the state-of-the-art progress of foundation models in robot learning and future research should focus on multimodal interaction especially dynamics data, exclusive foundation models for robots, and AI alignment, etc.

  • 8 authors
·
Nov 24, 2023

SpectralGPT: Spectral Foundation Model

The foundation model has recently garnered significant attention due to its potential to revolutionize the field of visual representation learning in a self-supervised manner. While most foundation models are tailored to effectively process RGB images for various visual tasks, there is a noticeable gap in research focused on spectral data, which offers valuable information for scene understanding, especially in remote sensing (RS) applications. To fill this gap, we created for the first time a universal RS foundation model, named SpectralGPT, which is purpose-built to handle spectral RS images using a novel 3D generative pretrained transformer (GPT). Compared to existing foundation models, SpectralGPT 1) accommodates input images with varying sizes, resolutions, time series, and regions in a progressive training fashion, enabling full utilization of extensive RS big data; 2) leverages 3D token generation for spatial-spectral coupling; 3) captures spectrally sequential patterns via multi-target reconstruction; 4) trains on one million spectral RS images, yielding models with over 600 million parameters. Our evaluation highlights significant performance improvements with pretrained SpectralGPT models, signifying substantial potential in advancing spectral RS big data applications within the field of geoscience across four downstream tasks: single/multi-label scene classification, semantic segmentation, and change detection.

  • 14 authors
·
Nov 13, 2023

Molecular-driven Foundation Model for Oncologic Pathology

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances, foundation models are still limited in their ability to encode the entire gigapixel whole-slide images without additional training and often lack complementary multimodal data. Here, we introduce Threads, a slide-level foundation model capable of generating universal representations of whole-slide images of any size. Threads was pre-trained using a multimodal learning approach on a diverse cohort of 47,171 hematoxylin and eosin (H&E)-stained tissue sections, paired with corresponding genomic and transcriptomic profiles - the largest such paired dataset to be used for foundation model development to date. This unique training paradigm enables Threads to capture the tissue's underlying molecular composition, yielding powerful representations applicable to a wide array of downstream tasks. In extensive benchmarking across 54 oncology tasks, including clinical subtyping, grading, mutation prediction, immunohistochemistry status determination, treatment response prediction, and survival prediction, Threads outperformed all baselines while demonstrating remarkable generalizability and label efficiency. It is particularly well suited for predicting rare events, further emphasizing its clinical utility. We intend to make the model publicly available for the broader community.

  • 18 authors
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Jan 27