| id,variant,gene,phenotype,evidence_pack,claim,evidence_binding_map,evidence_gaps,claim_overreach_flags,confidence_calibration,notes,constraints,gold_checklist | |
| VEI-T01,"rs222222","GENE10","asthma","GWAS hit p=1e-7 OR 1.03. No fine-mapping. No functional. In silico predicts enhancer.","This variant is causal for asthma.","Binding: weak association only.","No causal resolution; no functional; tiny effect size.","GWAS treated as causal; in silico treated as proof.","Very low confidence. Association only.","Classic causality creep","Under 220 words.","map+gaps+flags+calibration" | |
| VEI-T02,"c.77A>T (p.Glu26Val)","GENE11","metabolic disorder","Absent in gnomAD. Two affected siblings. Parents carriers. No functional yet.","Pathogenic variant.","Binding: segregation supports recessive; rarity supports.","Missing: functional confirmation; phenotype match details.","Pathogenic claim may be early; better as likely pathogenic with caveats.","Moderate confidence with caveats.","Borderline classification","Under 220 words.","map+gaps+flags+calibration" | |